Degenerative joint lesions in cynomolgus monkeys (Macaca fascicularis)

Joint BSTP/ESTP Toxicologic Pathology Congress 2025 -- Cynomolgus monkeys are used in toxicity studies because of their physiological similarity to humans, with older animals being used in studies in which sexual maturity is a prerequisite. Spontaneous degenerative joint disease (DJD) is known in adult and advanced age monkeys, but detailed descriptions and publications are rare.